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Andarine
CAS No. 401900-40-1
Andarine( GTx-007 | S-4 | GTx007 )
Catalog No. M14376 CAS No. 401900-40-1
Andarine (S-4;GTx007) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 4 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 42 | In Stock |
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| 5MG | 38 | In Stock |
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| 10MG | 57 | In Stock |
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| 25MG | 86 | In Stock |
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| 50MG | 114 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameAndarine
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NoteResearch use only, not for human use.
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Brief DescriptionAndarine (S-4;GTx007) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 4 nM.
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DescriptionAndarine (S-4;GTx007) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 4 nM, efficaciously stimulated AR-mediated reporter gene expression; demonstrates in vivo androgenic and anabolic activity, stimulates the anabolic organs more than the androgenic organs; improves muscle strength and body composition and prevents bone loss in orchidectomized rats.(In Vivo):GTx-007 (S-4) is only a partial agonist in the prostate and seminal vesicles, restoring them to 33.8 and 28.2% of intact animals, respectively.GTx-007 significantly increased uterine expression of Wnt4 and Wnt7a.
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In Vitro——
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In VivoGTx-007 (S-4) is only a partial agonist in the prostate and seminal vesicles, restoring them to 33.8 and 28.2% of intact animals, respectively.GTx-007 significantly increased uterine expression of Wnt4 and Wnt7a. Animal Model:Female C57BL/6J mice.Dosage:0.5?mg/mouse.Administration:Seven daily subcutaneous injections.Result:Resulted in a highly heterogeneous pattern of AR expression in all compartments, with a significant increase of AR-positive cells in the luminal epithelium compared to VC.Had approximately ten glands per uterine cross-section within an endometrium, with a compact stroma, consistent with overall endogenous steroid depletion.
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SynonymsGTx-007 | S-4 | GTx007
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PathwayEndocrinology/Hormones
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TargetAndrogen Receptor (AR)
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RecptorAndrogenReceptor
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number401900-40-1
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Formula Weight441.3579
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Molecular FormulaC19H18F3N3O6
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(NC1=CC=C([N+]([O-])=O)C(C(F)(F)F)=C1)[C@@](C)(O)COC2=CC=C(NC(C)=O)C=C2
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Chemical NamePropanamide, 3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-, (2S)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kearbey JD, et al. Xenobiotica. 2004 Mar;34(3):273-80.
2. Gao W, et al. Endocrinology. 2005 Nov;146(11):4887-97.
3. Yin D, et al. J Pharmacol Exp Ther. 2003 Mar;304(3):1334-40.
4. Kearbey JD, et al. Pharm Res. 2007 Feb;24(2):328-35.
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