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MS7972
CAS No. 352553-42-5
MS7972( MS 7972 )
Catalog No. M14203 CAS No. 352553-42-5
MS7972 is a small molecules that blocks p53 and CREB binding protein (CBP) association.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 119 | In Stock |
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| 5MG | 107 | In Stock |
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| 10MG | 183 | In Stock |
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| 25MG | 312 | In Stock |
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| 50MG | 440 | In Stock |
|
| 100MG | 603 | In Stock |
|
| 200MG | 812 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMS7972
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NoteResearch use only, not for human use.
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Brief DescriptionMS7972 is a small molecules that blocks p53 and CREB binding protein (CBP) association.
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DescriptionMS7972 is a small molecules that blocks p53 and CREB binding protein (CBP) association; completely blocks CBP BRD/p53-AcK382 interactions at 50 uM, results in loss of p53 phosphorylation at Ser15 as well as acetylation at Lys382; causes a dramatic decrease of the doxorubicin-induced p53 increase in U2OS cells.
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In VitroAddition of MS7972 to the CBP BRD results in emission at 445 nm and quenching of the CBP BRD due to resonance energy transfer.
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In Vivo——
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SynonymsMS 7972
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PathwayApoptosis
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TargetMDM2-p53
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RecptorMDM2-p53
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Research Area——
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Indication——
Chemical Information
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CAS Number352553-42-5
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Formula Weight227.263
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Molecular FormulaC14H13NO2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (440.02 mM)
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SMILESO=C1C(N(C(C)=O)C2=C3C=CC=C2)=C3CCC1
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Chemical Name9-Acetyl-3,4-dihydro-2H-carbazol-1-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Sachchidanand, et al. Chem Biol. 2006 Jan;13(1):81-90.
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