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BMS-394136
CAS No. 343246-73-1
BMS-394136( BMS394136 )
Catalog No. M14168 CAS No. 343246-73-1
BMS-394136 is a potent, selective IKur/Kv1.5inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 614 | In Stock |
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| 10MG | 873 | In Stock |
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| 25MG | 1311 | In Stock |
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| 50MG | 1730 | In Stock |
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| 100MG | 2316 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | 4585 | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameBMS-394136
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NoteResearch use only, not for human use.
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Brief DescriptionBMS-394136 is a potent, selective IKur/Kv1.5inhibitor.
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DescriptionBMS-394136 is a potent, selective IKur/Kv1.5inhibitor, increases atrial action potential duration (APD) and prolongs AERP but not VERP in both rabbits and beagles.Heart Arrhythmia Phase 1 Discontinued.
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In Vitro——
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In Vivo——
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SynonymsBMS394136
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PathwayCell Cycle/DNA Damage
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TargetPotassium Channel
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RecptorPotassium Channel
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Research AreaCardiovascular Disease
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IndicationHeart Arrhythmia
Chemical Information
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CAS Number343246-73-1
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Formula Weight471.357
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Molecular FormulaC24H21Cl2FN4O
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Purity>98% (HPLC)
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Solubility——
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SMILESCC1=C([C@H](n2c(ccn2)N1)c3ccc(c(c3)Cl)Cl)C(=O)N4CCC[C@H]4c5ccc(cc5)F
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Chemical NamePyrrolidine, 1-[[(7R)-7-(3,4-dichlorophenyl)-4,7-dihydro-5-methylpyrazolo[1,5-a]pyrimidin-6-yl]carbonyl]-2-(4-fluorophenyl)-, (2S)- (9CI)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Dezhi Xing, et al. Abstract 2515: A Selective IKur Blocker, BMS-394136 Selectively Prolongs Atrial APD and Refractoriness in Beagles and Rabbits. Circulation. 2009;120:S654.
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