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Depofemin
CAS No. 313-06-4
Depofemin( Estradiol cypionate | β-Estradiol 17-cypionate )
Catalog No. M14003 CAS No. 313-06-4
Estradiol cypionate is the 17 β-cyclopentylpropinate ester of estradiol, which inhibits ET-1 synthesis via estrogen receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | 29 | In Stock |
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| 500MG | 43 | In Stock |
|
| 1G | 73 | In Stock |
|
Biological Information
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Product NameDepofemin
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NoteResearch use only, not for human use.
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Brief DescriptionEstradiol cypionate is the 17 β-cyclopentylpropinate ester of estradiol, which inhibits ET-1 synthesis via estrogen receptor.
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DescriptionEstradiol cypionate is the 17 β-cyclopentylpropinate ester of estradiol, which inhibits ET-1 synthesis via estrogen receptor.
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In VitroWestern Blot Analysis Cell Line:MGC803, SGC7901, and BGC823 cells Concentration:10-25 μM Incubation Time:48 h Result:Increased protein level of cleaved caspase-3 and PARP.Decreased protein levels of AKT, p-AKT, p-mTOR, p-S6K, and p-4E-BP1.
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In VivoAnimal Model:MGC803 nude mice tumor model.Dosage:50-100?mg/kg Administration:i.p., every other day Result:Inhibited tumor growth.Increased Cleaved caspase-3 expression, decreased Ki67, AKT and p-AKT in tumors.
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SynonymsEstradiol cypionate | β-Estradiol 17-cypionate
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PathwayEndocrinology/Hormones
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TargetEstrogen Receptor/ERR
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RecptorER
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Research AreaEndocrinology
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Indication——
Chemical Information
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CAS Number313-06-4
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Formula Weight396.58
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Molecular FormulaC26H36O3
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Purity>98% (HPLC)
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SolubilityEthanol: 55 mg/mL (138.69 mM); DMSO: 79 mg/mL (199.21 mM)
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SMILESO=C(O[C@H]1CC[C@@]2([H])[C@]3([H])CCC4=C(C=CC(O)=C4)[C@@]3([H])CC[C@]12C)CCC5CCCC5
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Chemical NameCyclopentanepropionic acid, 3-hydroxyestra-1,3,5(10)-trien-17beta-yl ester
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Oriowo MA, et al. Contraception, 1980, 21(4), 415-424.
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