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Stugeron
CAS No. 298-57-7
Stugeron( Cinnarizine | Stugeron | Dimitronal | Stutgin | Dimitron | Folcodal | Dihydrochloride Cinnarizine | Dimitronal )
Catalog No. M13913 CAS No. 298-57-7
Cinnarizine is a drug derivative of piperazine, and characterized as an antihistamine and a calcium channel blocker.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | 27 | In Stock |
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Biological Information
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Product NameStugeron
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NoteResearch use only, not for human use.
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Brief DescriptionCinnarizine is a drug derivative of piperazine, and characterized as an antihistamine and a calcium channel blocker.
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DescriptionCinnarizine is a drug derivative of piperazine, and characterized as an antihistamine and a calcium channel blocker, it is also known to promote cerebral blood flow, and so is used to treat cerebral apoplexy, post-trauma cerebral symptoms, and cerebral arteriosclerosis.
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In Vitro——
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In Vivo——
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SynonymsCinnarizine | Stugeron | Dimitronal | Stutgin | Dimitron | Folcodal | Dihydrochloride Cinnarizine | Dimitronal
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PathwayGPCR/G Protein
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TargetCalcium Channel
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RecptorCalcium Channel| H1 receptor
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Research AreaCardiovascular Disease
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Indication——
Chemical Information
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CAS Number298-57-7
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Formula Weight368.51
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Molecular FormulaC26H28N2
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Purity>98% (HPLC)
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SolubilitySoluble in DMSO
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SMILESC1CN(CCN1C/C=C/C2=CC=CC=C2)C(C3=CC=CC=C3)C4=CC=CC=C4
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Chemical Name1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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DS16570511
DS16570511 is a cellular osmotic inhibitor of mitochondrial calcium monoab, which blocks MCU or MICU1-dependent Ca2+ influx.DS16570511 dose - dependent inhibition of serum-induced mitochondrial Ca2+ influx in HEK293A cells with IC50 of 7 M.DS16570511 inhibits the uptake of isolated Ca2+. mitochondria from human cells, rat heart and pig heart.
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(S)-(-)-Bay-K-8644
(S)-(-)-Bay-K-8644 is an agonist of L-type Ca2+ channel and activates Ba2+ currents with an EC50 of 32 nM.
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SR33805
SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively)Acute treatment with SR33805 restored the MI-altered cell shortening without affecting the Ca(2+) transient amplitude, suggesting an increase of myofilament Ca(2+) sensitivity in MI myocytes.?
