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FH1
CAS No. 2719-05-3
FH1( BRD-K4477 )
Catalog No. M13831 CAS No. 2719-05-3
FH1 (BRD-K4477) is a small molecule, which promotes differentiation of iPS-derived hepatocytes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 38 | In Stock |
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| 25MG | 74 | In Stock |
|
| 50MG | 133 | In Stock |
|
| 100MG | 237 | In Stock |
|
| 200MG | 308 | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameFH1
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NoteResearch use only, not for human use.
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Brief DescriptionFH1 (BRD-K4477) is a small molecule, which promotes differentiation of iPS-derived hepatocytes.
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DescriptionFH1 (BRD-K4477) is a small molecule, which promotes differentiation of iPS-derived hepatocytes.
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In VitroFH1 (NSC 12407, 5 μg/mL, 0-40 days) enhances hepatic maturation and maintain the hepatic differentiation state of hiPSC-HLCs. RT-PCRCell Line:hiPSC-HLCs in the differentiated hepatic state.Concentration:5 μg/mL.Incubation Time:0-40 days.Result:Kept more than 50% hiPSC-HLCs to produce the four factors till day 40.Can help hiPSC-HLCs to maintain a relatively mature hepatic differentiation state for about 40 days.Maintained a higher level of hALB in the supernatant than that in controls.Maintained relatively high mRNA levels of hNTCP, hRXR, hHNF4α, and hALB for over functional small molecule FH1 can help hiPSC-HLCs to maintain a relatively mature hepatic differentiation state for about 40 days.
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In Vivo——
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SynonymsBRD-K4477
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PathwayOthers
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TargetOther Targets
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RecptoriPS-derived hepatocytes
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number2719-05-3
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Formula Weight282.34
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Molecular FormulaC17H18N2O2
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Purity>98% (HPLC)
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SolubilityDMSO: 56 mg/mL (198.34 mM)
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SMILESCC(=O)NC1=CC=C(CC2=CC=C(NC(C)=O)C=C2)C=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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