Indazole

Research use only, not for human use.

Indazole, also called benzpyrazole or isoindazone, is a heterocyclic aromatic organic compound.

Indazole, also called benzpyrazole or isoindazone, is a heterocyclic aromatic organic compound. Indazole derivatives display a broad variety of biological activities.

Indazole compounds possess potential anticancer activity, and indazole-based agents such as, Axitinib (HY-10065), Lonidamine (HY-B0486) and Pazopanib (HY-10208) have already been used for cancer research, demonstrating indazole compounds as useful templates for the development of novel anticancer agents.Indazoles show potent activities against neurological disorders by inhibiting the monoamine oxidase (MAO) and kinase enzymes like Glycogen synthase kinase 3 (GSK3), and leucinerich repeat kinase enzyme 2 (LRRK2). Various natural and synthetic indazole derivatives Nigellicine, Nigellamine, Nigellidine, Zanubrutinib (HY-101474A) and SCH772984 (HY-50846) showes prominent results to cure various gastrointestinal disorders.

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Membrane Transporter/Ion Channel

Sodium Channel

Sodium Channel

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271-44-3

118.14

C7H6N2

>98% (HPLC)

DMSO: > 10 mM

N1N=CC2=CC=CC=C12

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(-20℃)

With Ice Pack

≥ 2 years