Indapamide

CAS No. 26807-65-8

Indapamide( (±)-Indapamide )

Catalog No. M13818 CAS No. 26807-65-8

Indapamide is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Indapamide
  • Note
    Research use only, not for human use.
  • Brief Description
    Indapamide is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.
  • Description
    Indapamide is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.(In Vitro):Indapamide (0.1-500 mg/L; 20min) reduces total insulin secretory response to glucose infusions in isolated perfused rat pancreas.Indapamide (1-100 μM) increases osteoblast proliferation and decreased bone resorption.(In Vivo):Indapamide (1 mg/kg/d; gastric gavage for 8 weeks) lowers blood pressure in spontaneously hypertensive rats (SHRs).Indapamide (10 mg/kg/d) decreases pressor response to oxotremorine, noradrenaline, and tyramine in rats.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    (±)-Indapamide
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Potassium Channel
  • Recptor
    Potassium Channel
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    26807-65-8
  • Formula Weight
    365.84
  • Molecular Formula
    C16H16ClN3O3S
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 73 mg/mL (199.54 mM); DMSO: 73 mg/mL (199.54 mM)
  • SMILES
    O=C(NN1C(C)CC2=C1C=CC=C2)C3=CC=C(Cl)C(S(=O)(N)=O)=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Pedersen EB, et al. Eur J Clin Pharmacol, 1984. 26(5): p. 543-7.
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