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5F 203

CAS No. 260443-89-8

5F 203( 5F-203 | 5F203 | NSC 703786 | NSC703786 )

Catalog No. M13790 CAS No. 260443-89-8

A potent, selective antitumour agent through activation the aryl hydrocarbon receptor (AhR) pathway.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 36 In Stock
5MG 37 In Stock
10MG 59 In Stock
25MG 119 In Stock
50MG 178 In Stock
100MG 257 In Stock
200MG 365 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    5F 203
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, selective antitumour agent through activation the aryl hydrocarbon receptor (AhR) pathway.
  • Description
    A potent, selective antitumour agent through activation the aryl hydrocarbon receptor (AhR) pathway; causes MCF-7 sensitive cells to arrest in G(1) and S phase, and induces DNA adduct formation, in contrast to AhR-deficient AH(R100) variant MCF-7 cells, induces CYP1A1 and CYP1B1 transcription; L-lysylamide prodrug Phortress (NSC 710305) demonstrats antitumor activity in vivo.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    5F-203 | 5F203 | NSC 703786 | NSC703786
  • Pathway
    Endocrinology/Hormones
  • Target
    AhR
  • Recptor
    AhR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    260443-89-8
  • Formula Weight
    258.314
  • Molecular Formula
    C14H11FN2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (387.13 mM)
  • SMILES
    CC1=C(C=CC(=C1)C2=NC3=C(S2)C=CC(=C3)F)N
  • Chemical Name
    2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bradshaw TD, et al. Mol Cancer Ther. 2002 Feb;1(4):239-46. 2. Gilbert J, et al. Mol Pharmacol. 2017 Dec 21. pii: mol.117.109827. 3. Trapani V, et al. Br J Cancer. 2003 Feb 24;88(4):599-605. 4. Leong CO, et al. Br J Cancer. 2003 Feb 10;88(3):470-7.
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