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Isomangiferin
CAS No. 24699-16-9
Isomangiferin( —— )
Catalog No. M13720 CAS No. 24699-16-9
Isomangiferin is the major tetracyclic oxindole alkaloid components of Uncaira species, inhibits NMDA receptor with IC50 of 43.2 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 110 | In Stock |
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| 10MG | 178 | In Stock |
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| 25MG | 296 | In Stock |
|
| 50MG | 443 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameIsomangiferin
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NoteResearch use only, not for human use.
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Brief DescriptionIsomangiferin is the major tetracyclic oxindole alkaloid components of Uncaira species, inhibits NMDA receptor with IC50 of 43.2 uM.
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DescriptionIsomangiferin is the major tetracyclic oxindole alkaloid components of Uncaira species, inhibits NMDA receptor with IC50 of 43.2 uM, also blocks calcium channel; also effectively blocks the EphA4-dependent signaling in hippocampal neurons, reduces the EphA4 activity effectively in the hippocampus of APP/PS1 transgenic mice after oral administration, restores the impaired long-term potentiation in transgenic mouse models of AD.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetiGluR
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RecptorAntiviral|Free radical scavengers
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number24699-16-9
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Formula Weight422.3396
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Molecular FormulaC19H18O11
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESC1=C2C(=CC(=C1O)O)OC3=C(C2=O)C(=CC(=C3C4C(C(C(C(O4)CO)O)O)O)O)O
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Chemical Name4-beta-D-Glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.?Kang TH, et al. Eur J Pharmacol. 2002 Nov 22;455(1):27-34.
2.?Kang TH, et al. Life Sci. 2004 Dec 3;76(3):331-43.
3.?Fu AK, et al. Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9959-64.
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