Isoconazole nitrate

Research use only, not for human use.

Isoconazole nitrate (Travogen) is an azole antifungal reagent.

Isoconazole nitrate (Travogen) is an azole antifungal reagent.(In Vitro):Isoconazole nitrate also exerts several other effects on the fungal membrane, which are independent of inhibition of the ergosterol synthesis. Isoconazole nitrate (ISN) causes a rapid reduction of cellular adenosine triphosphate (ATP) within 10 min of in vitro exposure.Isoconazole nitrate (1, 10 μg/mL) induces a blockade of cell division in vitro by its action on synthesis and organisation of the cell membrane. Isoconazole nitrate (50, 100 μg/mL), ISN induced necrosis and death of fungal cells.

Isoconazole nitrate also exerts several other effects on the fungal membrane, which are independent of inhibition of the ergosterol synthesis. Isoconazole nitrate (ISN) causes a rapid reduction of cellular adenosine triphosphate (ATP) within 10 min of in vitro exposure.Isoconazole nitrate (1, 10 μg/mL) induces a blockade of cell division in vitro by its action on synthesis and organisation of the cell membrane. Isoconazole nitrate (50, 100 μg/mL), ISN induced necrosis and death of fungal cells.

——

——

Others

Other Targets

Others

Infection

——

24168-96-5

479.14

C18H14Cl4N2O·HNO3

>98% (HPLC)

Ethanol: 4 mg/mL (8.34 mM); DMSO: 41 mg/mL (85.56 mM)

O[N+]([O-])=O.ClC1=CC(Cl)=C(C=C1)C(CN1C=CN=C1)OCC1=C(Cl)C=CC=C1Cl

——

(-20℃)

With Ice Pack

≥ 2 years