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Guanabenz acetate
CAS No. 23256-50-0
Guanabenz acetate( Wy8678 acetate )
Catalog No. M13664 CAS No. 23256-50-0
An α2 adrenergic receptor that is used as an antihypertensive drug.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | 28 | In Stock |
|
| 500MG | 37 | In Stock |
|
| 1G | 52 | In Stock |
|
Biological Information
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Product NameGuanabenz acetate
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NoteResearch use only, not for human use.
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Brief DescriptionAn α2 adrenergic receptor that is used as an antihypertensive drug.
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DescriptionAn α2 adrenergic receptor that is used as an antihypertensive drug; has been proposed to exert protective effects against misfolding by interfering with eIF2α-P dephosphorylation through selective disruption of a PP1-PPP1R15A holophosphatase complex; also has antiparasitic activity against replicative stages of Toxoplasma.Hypertension Approved(In Vitro):Guanabenz is an alpha agonist of the alpha-2 type that is used as an antihypertensive drug. It is used to treat high blood pressure (hypertension).
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In VitroGuanabenz is an alpha agonist of the alpha-2 type that is used as an antihypertensive drug. It is used to treat high blood pressure (hypertension).
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In Vivo——
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SynonymsWy8678 acetate
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PathwayGPCR/G Protein
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TargetAdrenergic Receptor
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Recptorα2A-adrenergic receptor| α2B-adrenergic receptor| α2C-adrenergic receptor
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Research AreaCardiovascular Disease
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IndicationHypertension
Chemical Information
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CAS Number23256-50-0
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Formula Weight291.1339
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Molecular FormulaC10H12Cl2N4O2
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 51 mg/ml
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SMILESNC(N/N=C/C1=C(Cl)C=CC=C1Cl)=N.CC(O)=O
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Chemical NameHydrazinecarboximidamide, 2-[(2,6-dichlorophenyl)methylene]-, acetate (1:1)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Das I, et al. Science. 2015 Apr 10;348(6231):239-42.
2. Crespillo-Casado A, et al. Elife. 2017 Apr 27;6. pii: e26109.
3. Benmerzouga I, et al. Antimicrob Agents Chemother. 2015 Nov;59(11):6939-45.
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