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Benfotiamine
CAS No. 22457-89-2
Benfotiamine( Benzoylthiamine monophosphate )
Catalog No. M13604 CAS No. 22457-89-2
Benfotiamine, the lipid-soluble thiamine derivative used as a treatment for diabetic neuropathy.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 83 | In Stock |
|
| 100MG | 31 | In Stock |
|
| 200MG | 45 | In Stock |
|
| 500MG | 73 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBenfotiamine
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NoteResearch use only, not for human use.
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Brief DescriptionBenfotiamine, the lipid-soluble thiamine derivative used as a treatment for diabetic neuropathy.
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DescriptionBenfotiamine, the lipid-soluble thiamine derivative used as a treatment for diabetic neuropathy, can inhibit three major pathways(the hexosamine pathway, the advanced glycation end product (AGE) formation pathway and the diacylglycerol (DAG)protein kinase C (PKC) pathway）of hyperglycemic damage and prevent experimental diabetic retinopathy. Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1) for treating sciatica and other painful nerve conditions. More effective at increasing thiamin levels in blood and tissues than water-soluble salts like the previous vitamin B1.
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In Vitro——
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In Vivo——
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SynonymsBenzoylthiamine monophosphate
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number22457-89-2
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Formula Weight466.46
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Molecular FormulaC19H23N4O6PS
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Purity>98% (HPLC)
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SolubilitySoluble in DMSO
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SMILESO=C(S/C(CCOP(O)(O)=O)=C(N(CC1=CN=C(C)N=C1N)C=O)/C)C2=CC=CC=C2
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Chemical Name(Z)-S-(2-(N-((4-amino-2-methylpyrimidin-5-yl)methyl)formamido)-5-(phosphonooxy)pent-2-en-3-yl) benzothioate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Bozic I, et al. PLoS One. 2015 Feb 19;10(2):e0118372.
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