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BI-3812
CAS No. 2166387-64-8
BI-3812( BI3812 | BI 3812 )
Catalog No. M13458 CAS No. 2166387-64-8
A highly potent and efficacious BCL6 inhibitor that potently inhibits the interaction of the BTB/POZ domain of BCL6 with several co-repressors in vitro with IC50 of <3 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 307 | In Stock |
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| 2MG | 157 | In Stock |
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| 5MG | 250 | In Stock |
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| 10MG | 425 | In Stock |
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| 25MG | 702 | In Stock |
|
| 50MG | 918 | In Stock |
|
| 100MG | 1293 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBI-3812
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NoteResearch use only, not for human use.
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Brief DescriptionA highly potent and efficacious BCL6 inhibitor that potently inhibits the interaction of the BTB/POZ domain of BCL6 with several co-repressors in vitro with IC50 of <3 nM.
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DescriptionA highly potent and efficacious BCL6 inhibitor that potently inhibits the interaction of the BTB/POZ domain of BCL6 with several co-repressors in vitro with IC50 of <3 nM; inhibits the BCL6/Co-repressor complex formation with IC50 of 40 nM in vitro.
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In Vitro——
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In Vivo——
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SynonymsBI3812 | BI 3812
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PathwayAngiogenesis
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TargetBcl-2
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RecptorBcl-2
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number2166387-64-8
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Formula Weight558.036
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Molecular FormulaC26H32ClN7O5
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Purity>98% (HPLC)
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SolubilityDMSO : 20.83 mg/mL 37.33 mM; H2O : < 0.1 mg/mL
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SMILESO=C(C1CCN(C2=NC=C(Cl)C(NC3=CC4=C(N(C)C(C(OCC(NC)=O)=C4)=O)C(OC)=C3)=N2)CC1)N(C)C
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Chemical Name1-(5-chloro-4-((8-methoxy-1-methyl-3-(2-(methylamino)-2-oxoethoxy)-2-oxo-1,2-dihydroquinolin-6-yl)amino)pyrimidin-2-yl)-N,N-dimethylpiperidine-4-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kerres N, et al. Cell Rep. 2017 Sep 19;20(12):2860-2875.
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