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CBP bromodomain inhibitor
CAS No. 2161356-61-0
CBP bromodomain inhibitor( —— )
Catalog No. M13447 CAS No. 2161356-61-0
a potent, selective CBP bromodomain inhibitor with IC50 of 69 nM, displays exquisite selectivity over BRD4(1) (IC50=18 uM) and the broader bromodomain family.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameCBP bromodomain inhibitor
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NoteResearch use only, not for human use.
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Brief Descriptiona potent, selective CBP bromodomain inhibitor with IC50 of 69 nM, displays exquisite selectivity over BRD4(1) (IC50=18 uM) and the broader bromodomain family.
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Descriptiona potent, selective CBP bromodomain inhibitor with IC50 of 69 nM, displays exquisite selectivity over BRD4(1) (IC50=18 uM) and the broader bromodomain family.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetBromodomain
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RecptorBromodomain
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Research Area——
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Indication——
Chemical Information
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CAS Number2161356-61-0
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Formula Weight426.486
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Molecular FormulaC22H20F2N4OS
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name5-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-3-methylbenzo[d]thiazol-2(3H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bronner SM, et al. J Med Chem. 2017 Dec 28;60(24):10151-10171.
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