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XDM-CBP
CAS No. 2138461-99-9
XDM-CBP( XDM CBP )
Catalog No. M13410 CAS No. 2138461-99-9
A highly potent and selective inhibitor of CBP/p300 bromodomain with Kd of 0.23/0.47 uM respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1143 | Get Quote |
|
| 50MG | 2322 | Get Quote |
|
| 100MG | 3060 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameXDM-CBP
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NoteResearch use only, not for human use.
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Brief DescriptionA highly potent and selective inhibitor of CBP/p300 bromodomain with Kd of 0.23/0.47 uM respectively.
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DescriptionA highly potent and selective inhibitor of CBP/p300 bromodomain with Kd of 0.23/0.47 uM respectively, with high selectivity over all other BD families, including the BET family; exhibits antiproliferative effect on numerous cancer cell lines, in particular malignant melanoma, breast cancer, and leukemia (HL-60 and MCF-7 cells GI50=1.3 and 4.2 uM, respectively).
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In Vitro——
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In Vivo——
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SynonymsXDM CBP
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PathwayChromatin/Epigenetic
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TargetBromodomain
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RecptorBromodomain
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Research Area——
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Indication——
Chemical Information
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CAS Number2138461-99-9
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Formula Weight366.417
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Molecular FormulaC21H22N2O4
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C1=C(CC)C(C(C)=O)=C(C)N1)NCC2=C3C(O)=CC=CC3=CC=C2O
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Chemical Name4-acetyl-N-((2,8-dihydroxynaphthalen-1-yl)methyl)-3-ethyl-5-methyl-1H-pyrrole-2-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Hügle M, et al. Angew Chem Int Ed Engl. 2017 Aug 2. doi: 10.1002/anie.201705516.
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