BCL6 inhibitor 7
CAS No. 2097518-46-0
BCL6 inhibitor 7( BCL6-IN-7 | BCL6 IN 7 | BCL6IN7 | BCL6 inhibitor-7 )
Catalog No. M13307 CAS No. 2097518-46-0
A potent BCL6 protein-protein interaction inhibitor with Kd of 78 nM; exhibits an efficacy in cell-free and cellular PPI assays.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 128 | In Stock |
|
| 10MG | 227 | In Stock |
|
| 25MG | 426 | In Stock |
|
| 50MG | 668 | In Stock |
|
| 100MG | 977 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBCL6 inhibitor 7
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent BCL6 protein-protein interaction inhibitor with Kd of 78 nM; exhibits an efficacy in cell-free and cellular PPI assays.
-
DescriptionA potent BCL6 protein-protein interaction inhibitor with Kd of 78 nM; exhibits an efficacy in cell-free and cellular PPI assays (ELISA IC50= 480 nM, M2H IC50= 8.6 uM).
-
In Vitro——
-
In Vivo——
-
SynonymsBCL6-IN-7 | BCL6 IN 7 | BCL6IN7 | BCL6 inhibitor-7
-
PathwayAngiogenesis
-
TargetBcl-2
-
RecptorBcl-2
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2097518-46-0
-
Formula Weight366.809
-
Molecular FormulaC18H15ClN6O
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 5 mg/mL (13.63 mM)
-
SMILESO=C1NC2=C(C=C(NC3=NC(NCC4=CC=CN=C4)=NC=C3Cl)C=C2)C1
-
Chemical Name5-((5-Chloro-2-((pyridin-3-ylmethyl)amino)pyrimidin-4-yl)-amino)-1,3-dihydro-2H-indol-2-one
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Kamada Y, et al. J Med Chem. 2017 May 25;60(10):4358-4368.
molnova catalog
related products
-
BCL6-IN-3
BCL6-IN-3 is a potent BCL6 inhibitor with GI50 of 70 nM in SU-DHL4 cells. BCL6-in-3 regulates cell activation, differentiation, DNA damage and apoptosis, and has antitumor activity.
-
BI-5273
A negative control compound of BI-3802 and BI-3812, which are potent and efficacious BCL6 degrader and inhibitor, respectively.
-
Thevetiaflavone
Thevetiaflavone could up-regulate the expression of Bcl 2 and down-regulate that of Bax and caspase 3.
Cart
sales@molnova.com