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ML-241 hydrochloride
CAS No. 2070015-13-1
ML-241 hydrochloride( ML241 hydrochloride | ML 241 hydrochloride )
Catalog No. M13221 CAS No. 2070015-13-1
ML241 Hcl is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 31 | In Stock |
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| 5MG | 29 | In Stock |
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| 10MG | 44 | In Stock |
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| 25MG | 90 | In Stock |
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| 50MG | 138 | In Stock |
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| 100MG | 207 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameML-241 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionML241 Hcl is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM).
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DescriptionML241 Hcl is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM); blocks degradation of p97-dependent proteasome substrate with an IC50 of 3.5 uM; induces caspases 3 and 7 and potently blocks proliferation in HCT15 and SW403 cells.
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In Vitro——
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In Vivo——
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SynonymsML241 hydrochloride | ML 241 hydrochloride
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PathwayProteasome/Ubiquitin
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Targetp97
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Recptorp97
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number2070015-13-1
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Formula Weight408.9238
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Molecular FormulaC23H25ClN4O
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 34 mg/mL
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SMILES[H]Cl.C1(N2C3=CC=CC=C3OCC2)=NC(NCC4=CC=CC=C4)=C5CCCCC5=N1
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Chemical Name4-Quinazolinamine, 2-(2,3-dihydro-4H-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydro-N-(phenylmethyl)-,hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chou TF, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
2. Chou TF, et al. ChemMedChem. 2013 Feb;8(2):297-312.
3. Fang CJ, et al. ChemMedChem. 2015 Jan;10(1):52-6.
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