Cart
sales@molnova.com
Piperlongumine
CAS No. 20069-09-4
Piperlongumine( Piplartine )
Catalog No. M13131 CAS No. 20069-09-4
A naturally occurring small molecule recently identified to be toxic selectively to cancer cells in vitro and in vivo.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 27 | In Stock |
|
| 25MG | 45 | In Stock |
|
| 50MG | 72 | In Stock |
|
| 100MG | 110 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePiperlongumine
-
NoteResearch use only, not for human use.
-
Brief DescriptionA naturally occurring small molecule recently identified to be toxic selectively to cancer cells in vitro and in vivo.
-
DescriptionA naturally occurring small molecule recently identified to be toxic selectively to cancer cells in vitro and in vivo; elevates cellular levels of reactive oxygen species (ROS) selectively in cancer cell lines, potently inhibits the growth of spontaneously formed malignant breast tumours and their associated metastases in mice; inhibits the STAT3 signal pathway in MM cells by binding directly to the STAT3 Cys712 residue.
-
In Vitro——
-
In Vivo——
-
SynonymsPiplartine
-
PathwayJAK/STAT Signaling
-
TargetSTAT
-
RecptorROS
-
Research AreaOther Indications
-
Indication——
Chemical Information
-
CAS Number20069-09-4
-
Formula Weight317.34
-
Molecular FormulaC17H19NO5
-
Purity>98% (HPLC)
-
SolubilityDMSO: 31.7 mg/mL (100 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble )
-
SMILESO=C1C=CCCN1C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)=O
-
Chemical Name5,6-dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-2(1H)-pyridinone
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Raj L, et al. Nature. 2011 Jul 13;475(7355):231-4.
2. Adams DJ, et al. Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15115-20.
3. Yao Y, et al. Oncotarget. 2016 Nov 8;7(45):73497-73508.
molnova catalog
related products
-
Oleanolic Acid
Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities.
-
ML116
A novel selective STAT3 inhibitor with IC50 of 4.2 uM.
-
STAT3-IN-B9
STAT3-IN-B9 is an inhibitor of abnormal STAT3 activation and inhibits the proliferation of tumor cells including MDA-MB-468, MDA-MB-231, and DU145.
