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Revaprazan
CAS No. 199463-33-7
Revaprazan( SB-641257 | YH-1885 )
Catalog No. M13113 CAS No. 199463-33-7
Revaprazan (SB-641257;YH-1885) is a potent potassium-competitive acid blocker (P-CAB) that inhibits H+,K+-ATPase in a reversible and K+-competitive manner.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameRevaprazan
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NoteResearch use only, not for human use.
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Brief DescriptionRevaprazan (SB-641257;YH-1885) is a potent potassium-competitive acid blocker (P-CAB) that inhibits H+,K+-ATPase in a reversible and K+-competitive manner.
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DescriptionRevaprazan (SB-641257;YH-1885) is a potent potassium-competitive acid blocker (P-CAB) that inhibits H+,K+-ATPase in a reversible and K+-competitive manner; reduces gastric acid secretion, also exerts anti-inflammatory action against Helicobacter pylori-induced COX-2 expression by inactivating Akt signaling.UlcerApproved.
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In Vitro——
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In Vivo——
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SynonymsSB-641257 | YH-1885
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PathwayMembrane Transporter/Ion Channel
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TargetProton Pump
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RecptorProton Pump
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Research AreaOther Indications
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IndicationUlcer
Chemical Information
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CAS Number199463-33-7
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Formula Weight362.44
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Molecular FormulaC22H23FN4
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Purity>98% (HPLC)
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Solubility——
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SMILESCC1N(C2=C(C)C(C)=NC(NC3=CC=C(F)C=C3)=N2)CCC4=C1C=CC=C4
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Chemical NameN-(4-fluorophenyl)-4,5-dimethyl-6-(1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)pyrimidin-2-amine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Li H, et al. Drug Metab Dispos. 2001 Jan;29(1):54-9.
2. Lee JS, et al. J Clin Biochem Nutr. 2012 Sep;51(2):77-83.
3. Inatomi N, et al. Pharmacol Ther. 2016 Dec;168:12-22.
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