CN-SAH( —— )

Catalog No. M13103 CAS No. 1985669-27-9

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

CN-SAH
Note

Research use only, not for human use.
Brief Description

CN-SAH is a potent and selective inhibitor of histone methyl transferase DOT1L with IC50 of 26 nM.
Description

CN-SAH is a potent and selective inhibitor of histone methyl transferase DOT1L with IC50 of 26 nM, displays >10-fold selectivity over DNMT1, PRMT3, PRMT5, and G9α.
In Vitro

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In Vivo

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Synonyms

——
Pathway

Chromatin/Epigenetic
Target

HMTase
Recptor

HMTase
Research Area

——
Indication

——

CAS Number

1985669-27-9
Formula Weight

408.433
Molecular Formula

C16H20N6O5S
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

S-(((2S,3R,4S,5R)-5-(4-amino-5-cyano-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)-L-homocysteine

1. Spurr SS, et al. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4518-22.

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