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Baloxavir Marboxil
CAS No. 1985606-14-1
Baloxavir Marboxil( S-033188 | Xofluza )
Catalog No. M13102 CAS No. 1985606-14-1
Baloxavir Marboxil (S-033188, Xofluza) is the prodrug of Baloxavir acid (S-033447) that potently and selectively inhibits the cap-dependent endonuclease within the polymerase PA subunit of influenza A and B viruses.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 38 | In Stock |
|
| 50MG | 49 | In Stock |
|
| 100MG | 82 | In Stock |
|
| 500MG | 311 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBaloxavir Marboxil
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NoteResearch use only, not for human use.
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Brief DescriptionBaloxavir Marboxil (S-033188, Xofluza) is the prodrug of Baloxavir acid (S-033447) that potently and selectively inhibits the cap-dependent endonuclease within the polymerase PA subunit of influenza A and B viruses.
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DescriptionBaloxavir Marboxil (S-033188, Xofluza) is the prodrug of Baloxavir acid (S-033447) that potently and selectively inhibits the cap-dependent endonuclease within the polymerase PA subunit of influenza A and B viruses. Influenza Approved(In Vitro):Baloxavir marboxil is a polymerase acidic protein (PA) endonuclease inhibitor.
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In VitroBaloxavir marboxil is a polymerase acidic protein (PA) endonuclease inhibitor.
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In Vivo——
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SynonymsS-033188 | Xofluza
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PathwayMicrobiology/Virology
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TargetInfluenza Virus
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RecptorInfluenza Virus
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Research AreaInfection
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IndicationInfluenza
Chemical Information
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CAS Number1985606-14-1
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Formula Weight571.552
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Molecular FormulaC27H23F2N3O7S
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 50 mg/mL 87.48 mM
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SMILESO=C(OCOC(C(C=C1)=O)=C(N1N([C@@H]2C3=CC=CC=C3SCC4=C(F)C(F)=CC=C24)[C@@]5([H])N6CCOC5)C6=O)OC
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Chemical Name({(12aR)-12-[(11S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl]-6,8-dioxo-3,4,6,8,12,12a-hexahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazin-7-yl}oxy)methyl methyl carbonate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Eleutheroside B1
Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities.
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CBS1117
CBS1117 is an inhibitor virus entry inhibitor(IC50 of 70 nM for influenza A virus), A/Puerto Rico/8/34 (H1N1).?It interferes with the hemagglutinin (HA)-mediated fusion process.CBS1117 which has a 50% inhibitory concentration of 70 nM and a selectivity index of ~4000 against A/Puerto Rico/8/34 (H1N1) infection in human lung epithelial cell line (A549).
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RO-7
RO-7 is a novel small molecule, broad-spectrum inhibitor of influenza acidic polymerase (PA) protein endonuclease activity with EC50 of 3.2-16 nM in MDCK cells.
