Baloxavir Marboxil( S-033188 | Xofluza )

Catalog No. M13102 CAS No. 1985606-14-1

COA

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HNMR

HPLC

MSDS

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Product Name

Baloxavir Marboxil
Note

Research use only, not for human use.
Brief Description

Baloxavir Marboxil (S-033188, Xofluza) is the prodrug of Baloxavir acid (S-033447) that potently and selectively inhibits the cap-dependent endonuclease within the polymerase PA subunit of influenza A and B viruses.
Description

Baloxavir Marboxil (S-033188, Xofluza) is the prodrug of Baloxavir acid (S-033447) that potently and selectively inhibits the cap-dependent endonuclease within the polymerase PA subunit of influenza A and B viruses. Influenza Approved(In Vitro):Baloxavir marboxil is a polymerase acidic protein (PA) endonuclease inhibitor.
In Vitro

Baloxavir marboxil is a polymerase acidic protein (PA) endonuclease inhibitor.
In Vivo

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Synonyms

S-033188 | Xofluza
Pathway

Microbiology/Virology
Target

Influenza Virus
Recptor

Influenza Virus
Research Area

Infection
Indication

Influenza

CAS Number

1985606-14-1
Formula Weight

571.552
Molecular Formula

C27H23F2N3O7S
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 50 mg/mL 87.48 mM
SMILES

O=C(OCOC(C(C=C1)=O)=C(N1N([C@@H]2C3=CC=CC=C3SCC4=C(F)C(F)=CC=C24)[C@@]5([H])N6CCOC5)C6=O)OC
Chemical Name

({(12aR)-12-[(11S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl]-6,8-dioxo-3,4,6,8,12,12a-hexahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazin-7-yl}oxy)methyl methyl carbonate

1. Omoto S, et al. Sci Rep. 2018 Jun 25;8(1):9633.

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