ZBMA-1

CAS No. 1975145-64-2

ZBMA-1( —— )

Catalog No. M13088 CAS No. 1975145-64-2

ZBMA-1 is a potent HIV-1 replication inhibitor (IC50=1.01 uM) that efficiently protects APOBEC3G protein by targeting Vif-APOBEC3G complex.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ZBMA-1
  • Note
    Research use only, not for human use.
  • Brief Description
    ZBMA-1 is a potent HIV-1 replication inhibitor (IC50=1.01 uM) that efficiently protects APOBEC3G protein by targeting Vif-APOBEC3G complex.
  • Description
    ZBMA-1 is a potent HIV-1 replication inhibitor (IC50=1.01 uM) that efficiently protects APOBEC3G protein by targeting Vif-APOBEC3G complex; protected APOBEC3G from Vif-mediated degradation in a dose-dependent manner and induced nonfunctional proviruses, blocked Vif binding to Elongin C, does not affect the interactions between Vif and APOBEC3G or CBF-β.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    HIV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1975145-64-2
  • Formula Weight
    325.169
  • Molecular Formula
    C15H9BrN4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    2-(1H-benzo[d]imidazol-2-yl)-3-(6-bromopyridin-3-yl)acrylonitrile

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhang S, et al. Antiviral Res. 2015 Oct;122:20-7.
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