ZBMA-1
CAS No. 1975145-64-2
ZBMA-1( —— )
Catalog No. M13088 CAS No. 1975145-64-2
ZBMA-1 is a potent HIV-1 replication inhibitor (IC50=1.01 uM) that efficiently protects APOBEC3G protein by targeting Vif-APOBEC3G complex.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameZBMA-1
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NoteResearch use only, not for human use.
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Brief DescriptionZBMA-1 is a potent HIV-1 replication inhibitor (IC50=1.01 uM) that efficiently protects APOBEC3G protein by targeting Vif-APOBEC3G complex.
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DescriptionZBMA-1 is a potent HIV-1 replication inhibitor (IC50=1.01 uM) that efficiently protects APOBEC3G protein by targeting Vif-APOBEC3G complex; protected APOBEC3G from Vif-mediated degradation in a dose-dependent manner and induced nonfunctional proviruses, blocked Vif binding to Elongin C, does not affect the interactions between Vif and APOBEC3G or CBF-β.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV
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Research Area——
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Indication——
Chemical Information
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CAS Number1975145-64-2
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Formula Weight325.169
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Molecular FormulaC15H9BrN4
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name2-(1H-benzo[d]imidazol-2-yl)-3-(6-bromopyridin-3-yl)acrylonitrile
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhang S, et al. Antiviral Res. 2015 Oct;122:20-7.
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