RIPA-56

CAS No. 1956370-21-0

RIPA-56( RIPA56 | RIPA 56 )

Catalog No. M13064 CAS No. 1956370-21-0

A highly potent, selective, stable Receptor-interacting protein 1 (RIP1) inhibitor with IC50 of 13 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 48 In Stock
5MG 30 In Stock
10MG 46 In Stock
25MG 82 In Stock
50MG 128 In Stock
100MG 209 In Stock
200MG 310 In Stock
500MG 520 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    RIPA-56
  • Note
    Research use only, not for human use.
  • Brief Description
    A highly potent, selective, stable Receptor-interacting protein 1 (RIP1) inhibitor with IC50 of 13 nM.
  • Description
    A highly potent, selective, stable Receptor-interacting protein 1 (RIP1) inhibitor with IC50 of 13 nM; shows good selectivity in kinase panel screening, and does not IDO activity ( at >200 uM); efficiently protects mice from mTNFα-induced multi-organ damage.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    RIPA56 | RIPA 56
  • Pathway
    Apoptosis
  • Target
    RIP kinase
  • Recptor
    RIP kinase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1956370-21-0
  • Formula Weight
    221.29546
  • Molecular Formula
    C13H19NO2
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    CCC(C)(C)C(N(O)CC1=CC=CC=C1)=O
  • Chemical Name
    Butanamide, N-hydroxy-2,2-dimethyl-N-(phenylmethyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ren Y, et al. J Med Chem. 2017 Feb 9;60(3):972-986.
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