RWJ-49815( RWJ 49815 | RWJ49815 )

Catalog No. M13029 CAS No. 193282-45-0

A potent bactericidal agent that inhibits the KinA autophosphorylation with IC50 of 1.6 uM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

RWJ-49815
Note

Research use only, not for human use.
Brief Description

A potent bactericidal agent that inhibits the KinA autophosphorylation with IC50 of 1.6 uM.
Description

A potent bactericidal agent that inhibits the KinA autophosphorylation with IC50 of 1.6 uM; inhibits the autophosphorylation of kinase A of the KinA-Spo0F two-component signal transduction system in vitro; suppresses growth of MRSA, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus pneumoniae (MICs=1-2 ug/ml); exhibits reduced resistance emergence in a laboratory passage experiment compared with quinolone and ciprofloxacin.
In Vitro

——
In Vivo

——
Synonyms

RWJ 49815 | RWJ49815
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

193282-45-0
Formula Weight

449.598
Molecular Formula

C30H31N3O
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

1-(4-(3,3,3-triphenylpropoxy)phenethyl)guanidine

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Barrett JF, et al. Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):5317-22. 2. Stephenson K, et al. J Biol Chem. 2000 Dec 8;275(49):38900-4. 3. Theodorou EC, et al. Cell Signal. 2011 Aug;23(8):1327-37.

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