Cart
sales@molnova.com
JAK3i
CAS No. 1918238-72-8
JAK3i( JAK3 inhibitor JAK3i )
Catalog No. M13007 CAS No. 1918238-72-8
JAK3i is a selective, covalent JAK3 kinase inhibitor with IC50 of 0.43 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 662 | In Stock |
|
| 5MG | 787 | In Stock |
|
| 10MG | 1074 | In Stock |
|
| 25MG | 1511 | In Stock |
|
| 50MG | 1841 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameJAK3i
-
NoteResearch use only, not for human use.
-
Brief DescriptionJAK3i is a selective, covalent JAK3 kinase inhibitor with IC50 of 0.43 nM.
-
DescriptionJAK3i is a selective, covalent JAK3 kinase inhibitor with IC50 of 0.43 nM, shows high selectivity (>3,000-fold) against the closely related kinase domains in JAK1, JAK2, or TYK2, displays 1,300-fold, 600-fold, and 50-fold over EGFR, ITK, and BTK respectively.
-
In Vitro——
-
In Vivo——
-
SynonymsJAK3 inhibitor JAK3i
-
PathwayAngiogenesis
-
TargetJAK
-
RecptorJAK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1918238-72-8
-
Formula Weight354.34
-
Molecular FormulaC18H15FN4O3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(C1=CNC2=NC=NC(C3=CC(NC(C=C)=O)=CC=C3F)=C21)OCC
-
Chemical NameEthyl 4-(5-acrylamido-2-fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylate
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Smith GA, et al. Nat Chem Biol. 2016 May;12(5):373-9.
molnova catalog
related products
-
SAR-20347
SAR-20347 (SAR20347) is a potent, selective inhibitor of JAK1 and Tyk2 with IC50 of 59 and 13 nM in TR-FRET assays.
-
CYT387
A potent and selective JAK1/JAK2 inhibitor with IC50 of 11/18 nM.
-
Fosifidancitinib
Fosifidancitinib is a potent inhibitor of JAK 1 and JAK 3.
