EPZ 025654

CAS No. 1888328-89-9

EPZ 025654( EPZ025654 | EPZ-025654 | GSK 35336023 )

Catalog No. M12957 CAS No. 1888328-89-9

EPZ025654 (GSK 35336023) is a potent, selective arginine methyltransferase CARM1 inhibitor with IC50 of 3 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    EPZ 025654
  • Note
    Research use only, not for human use.
  • Brief Description
    EPZ025654 (GSK 35336023) is a potent, selective arginine methyltransferase CARM1 inhibitor with IC50 of 3 nM.
  • Description
    EPZ025654 (GSK 35336023) is a potent, selective arginine methyltransferase CARM1 inhibitor with IC50 of 3 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    EPZ025654 | EPZ-025654 | GSK 35336023
  • Pathway
    Chromatin/Epigenetic
  • Target
    HMTase
  • Recptor
    HMTase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1888328-89-9
  • Formula Weight
    577.086
  • Molecular Formula
    C29H33ClN8O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O[C@H](CNC)COC1=CC=C(Cl)C(C2=NC(C3=C(C)ON=C3C)=C(C)C(N4CC5=NC(N6CCC6)=NC=C5C4)=N2)=C1
  • Chemical Name
    (R)-1-(3-(4-(2-(azetidin-1-yl)-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidin-6-yl)-6-(3,5-dimethylisoxazol-4-yl)-5-methylpyrimidin-2-yl)-4-chlorophenoxy)-3-(methylamino)propan-2-ol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Drew AE, et al. Sci Rep. 2017 Dec 21;7(1):17993.
molnova catalog
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