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PA-824
CAS No. 187235-37-6
PA-824( PA824 | PA 824 | Pretomanid | (S)-PA 824 )
Catalog No. M12898 CAS No. 187235-37-6
A anti-tuberculosis agent that inhibits the synthesis of protein and cell wall lipid; exhibits bactericidal activity against both replicating and static M. tuberculosis (MIC: 0.015-0.25 ug/mL).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 43 | In Stock |
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| 5MG | 39 | In Stock |
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| 10MG | 63 | In Stock |
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| 25MG | 90 | In Stock |
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| 50MG | 115 | In Stock |
|
| 100MG | 178 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePA-824
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NoteResearch use only, not for human use.
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Brief DescriptionA anti-tuberculosis agent that inhibits the synthesis of protein and cell wall lipid; exhibits bactericidal activity against both replicating and static M. tuberculosis (MIC: 0.015-0.25 ug/mL).
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DescriptionA anti-tuberculosis agent that inhibits the synthesis of protein and cell wall lipid; exhibits bactericidal activity against both replicating and static M. tuberculosis (MIC: 0.015-0.25 ug/mL); shows potent bactericidal activity against MDR M. tuberculosis and promising oral activity in animal infection models.
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In Vitro——
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In Vivo——
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SynonymsPA824 | PA 824 | Pretomanid | (S)-PA 824
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PathwayGPCR/G Protein
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TargetAntibacterial
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Recptortuberculosis
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number187235-37-6
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Formula Weight359.2574
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Molecular FormulaC14H12F3N3O5
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 33 mg/mL
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SMILESFC(F)(F)OC1=CC=C(C=C1)CO[C@H]2CN3C(OC2)=NC([N+]([O-])=O)=C3
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Chemical Name5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-, (6S)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Stover CK, et al. Nature. 2000 Jun 22;405(6789):962-6.
2. Tyagi S, et al. Antimicrob Agents Chemother. 2005 Jun;49(6):2289-93.
3. Lenaerts AJ, et al. Antimicrob Agents Chemother. 2005 Jun;49(6):2294-301.
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