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SUVN-502 mesylate
CAS No. 1791396-46-7
SUVN-502 mesylate( SUVN502 )
Catalog No. M12698 CAS No. 1791396-46-7
SUVN-502 (SUVN502) is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 125 | In Stock |
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| 5MG | 85 | In Stock |
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| 10MG | 140 | In Stock |
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| 25MG | 250 | In Stock |
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| 50MG | 368 | In Stock |
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| 100MG | 600 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSUVN-502 mesylate
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NoteResearch use only, not for human use.
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Brief DescriptionSUVN-502 (SUVN502) is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM.
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DescriptionSUVN-502 (SUVN502) is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM; shows high selectivity over 5-HT2A receptor and other 100 target sites; produces synergistic effects in extracellular levels of acetylcholine in the ventral hippocampus combined with donepezil and memantine; shows potential for treatment of Alzheimer's disease.Alzheimer Disease Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsSUVN502
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PathwayGPCR/G Protein
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research AreaNeurological Disease
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IndicationAlzheimer Disease
Chemical Information
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CAS Number1791396-46-7
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Formula Weight574.505
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Molecular FormulaC22H28BrN3O6S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (37.28 mM)
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SMILESCN1CCN(CC1)CC2=CN(C3=C2C=C(C=C3)OC)S(=O)(=O)C4=CC=CC=C4Br.CS(=O)(=O)O.CS(=O)(=O)O
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Chemical Name1-((2-bromophenyl)sulfonyl)-5-methoxy-3-((4-methylpiperazin-1-yl)methyl)-1H-indole methanesulfonate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Nirogi R, et al. J Med Chem. 2017 Mar 9;60(5):1843-1859.
2. Nirogi R, et al. J Pharm Biomed Anal. 2017 Apr 14;145:423-430.
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