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Revaprazan hydrochloride
CAS No. 178307-42-1
Revaprazan hydrochloride( SB-641257 | YH-1885 )
Catalog No. M12683 CAS No. 178307-42-1
Revaprazan (SB-641257;YH-1885) potent potassium-competitive acid blocker (P-CAB) that inhibits H+,K+-ATPase in a reversible and K+-competitive manner.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 33 | In Stock |
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| 25MG | 67 | In Stock |
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| 50MG | 104 | In Stock |
|
| 100MG | 163 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRevaprazan hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionRevaprazan (SB-641257;YH-1885) potent potassium-competitive acid blocker (P-CAB) that inhibits H+,K+-ATPase in a reversible and K+-competitive manner.
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DescriptionRevaprazan (SB-641257;YH-1885) potent potassium-competitive acid blocker (P-CAB) that inhibits H+,K+-ATPase in a reversible and K+-competitive manner; reduces gastric acid secretion, also exerts anti-inflammatory action against Helicobacter pylori-induced COX-2 expression by inactivating Akt signaling.Ulcer Approved.
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In Vitro——
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In Vivo——
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SynonymsSB-641257 | YH-1885
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PathwayMembrane Transporter/Ion Channel
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TargetProton Pump
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RecptorH+/K+-ATPase
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Research AreaOther Indications
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IndicationUlcer
Chemical Information
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CAS Number178307-42-1
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Formula Weight398.91
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Molecular FormulaC22H24ClFN4
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESCl.CC1N(CCc2ccccc12)c3nc(Nc4ccc(F)cc4)nc(C)c3C
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Chemical NameN-(4-fluorophenyl)-4,5-dimethyl-6-(1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)pyrimidin-2-amine hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Li H, et al. Drug Metab Dispos. 2001 Jan;29(1):54-9.
2. Lee JS, et al. J Clin Biochem Nutr. 2012 Sep;51(2):77-83.
3. Inatomi N, et al. Pharmacol Ther. 2016 Dec;168:12-22.
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