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Olinone
CAS No. 1770789-37-1
Olinone( Olinone )
Catalog No. M12666 CAS No. 1770789-37-1
Olinone is a selective inhibitor for the BET BRD1 with Kd of 3.4/3.7/8.6 uM for BRD4-BrD1/BRD3-BrD1/BRD2-BrD1, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
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| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameOlinone
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NoteResearch use only, not for human use.
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Brief DescriptionOlinone is a selective inhibitor for the BET BRD1 with Kd of 3.4/3.7/8.6 uM for BRD4-BrD1/BRD3-BrD1/BRD2-BrD1, respectively.
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DescriptionOlinone is a selective inhibitor for the BET BRD1 with Kd of 3.4/3.7/8.6 uM for BRD4-BrD1/BRD3-BrD1/BRD2-BrD1, respectively, shows high selectivity over BET BRD2 (Kd>300 uM); accelerates the progression of mouse primary oligodendrocyte progenitors toward differentiation.
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In Vitro——
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In Vivo——
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SynonymsOlinone
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PathwayChromatin/Epigenetic
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TargetBromodomain
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RecptorBromodomain
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Research Area——
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Indication——
Chemical Information
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CAS Number1770789-37-1
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Formula Weight299.374
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Molecular FormulaC17H21N3O2
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(NCCCCN1C(CCN2)=C(C2=O)C3=C1C=CC=C3)=O
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Chemical NameN-[4-(1-Oxo-1,2,3,4-tetrahydro-pyrido[4,3-b]indol-5-yl)-butyl]-acetamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Gacias M, et al. Chem Biol. 2014 Jul 17;21(7):841-54.
2. Chiang CM. Chem Biol. 2014 Jul 17;21(7):804-6.
3. Zhao L, et J Neuroinflammation. 2017 Jan 19;14(1):14.al.
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