Sutezolid

Research use only, not for human use.

An oxazolidinone antibiotic that possesses potent antituberculosis activity in vitro and in vivo.

An oxazolidinone antibiotic that possesses potent antituberculosis activity in vitro and in vivo; significantly shorten the duration of therapy for drug-susceptible as well as multidrug-resistant tuberculosis.Bacterial Infection Phase 2 Clinical(In Vitro):Sutezolid (PNU-100480) exhibits excellent in vitro activity against multiple clinical isolates of Mycobacterium avium complex (MIC’s=0.5-4 μg/mL).(In Vivo):Sutezolid (PNU-100480) is a thiomorpholinyl analog of linezolid with superior efficacy against M. tuberculosis in the hollow-fiber, mouse, and whole-blood models.

Sutezolid (PNU-100480) exhibits excellent in vitro activity against multiple clinical isolates of Mycobacterium avium complex (MIC’s=0.5-4 μg/mL).

Sutezolid (PNU-100480) is a thiomorpholinyl analog of linezolid with superior efficacy against M. tuberculosis in the hollow-fiber, mouse, and whole-blood models.

PNU-100480 | PNU100480 | PF-02341272 | PF02341272 | U-100480

GPCR/G Protein

Antibacterial

Antibacterial

Infection

Bacterial Infection

168828-58-8

353.4117

C16H20FN3O3S

>98% (HPLC)

10 mM in DMSO

CC(NC[C@H]1CN(C2=CC=C(N3CCSCC3)C(F)=C2)C(O1)=O)=O

Acetamide, N-[[(5S)-3-[3-fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-

(-20℃)

With Ice Pack

≥ 2 years