PD-1-IN-1( CA-170 | CA-170 | CA-170 | AUPM 170 | AUPM-170 | AUPM170 | PD-1-IN-1 )

Catalog No. M12554 CAS No. 1673534-76-3

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Product Name

PD-1-IN-1
Note

Research use only, not for human use.
Brief Description

PD-1-IN-1 is a small molecule inhibitor of programmed cell dealth-1 (PD-1).
Description

PD-1-IN-1 is a small molecule inhibitor of programmed cell dealth-1 (PD-1) extracted from patent WO 2015033299 A1, compound example 4.
In Vitro

CA-170 exhibits potent functional activity in rescuing T-cell proliferation and effector functions, while showing selectivity against other immune checkpoint proteins as well as in a broad panel of receptors and enzymes.
In Vivo

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Synonyms

CA-170 | CA-170 | CA-170 | AUPM 170 | AUPM-170 | AUPM170 | PD-1-IN-1
Pathway

Immunology/Inflammation
Target

PD-1/PD-L1
Recptor

PD-1/PD-L1
Research Area

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Indication

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CAS Number

1673534-76-3
Formula Weight

360.3232
Molecular Formula

C12H20N6O7
Purity

>98% (HPLC)
Solubility

DMSO: 28.5 mg/mL
SMILES

OC([C@H]([C@@H](O)C)NC(N[C@@H](CC(N)=O)C1=NC([C@@H](CO)N)=NO1)=O)=O
Chemical Name

L-Threonine, N-[[[(1S)-3-amino-1-[3-[(1R)-1-amino-2-hydroxyethyl]-1,2,4-oxadiazol-5-yl]-3-oxopropyl]amino]carbonyl]-

1. Patent WO 2015033299 A1.

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