Ibrutinib-biotin( —— )

Catalog No. M12294 CAS No. 1599432-18-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

Ibrutinib-biotin
Note

Research use only, not for human use.
Brief Description

A chemical probe that consists of Ibrutinib linked to biotin via a long chain linker.
Description

A chemical probe that consists of Ibrutinib linked to biotin via a long chain linker, has IC50 of 0.755-1.02 nM for Btk kinase; extracted from patent WO2014059368A1 Compound 1-5.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Tyrosine Kinase
Target

BTK
Recptor

BTK
Research Area

Cancer
Indication

——

CAS Number

1599432-18-4
Formula Weight

1097.374
Molecular Formula

C56H80N12O9S
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

CN(CCCCNC(=O)CCCC(=O)NCCCOCCOCCOCCCNC(=O)CCCCC1C2C(CS1)NC(=O)N2)CC=CC(=O)N3CCCC(C3)N4C5=NC=NC(=C5C(=N4)C6=CC=C(C=C6)OC7=CC=CC=C7)N
Chemical Name

Pentanediamide, N1-[4-[[4-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-4-oxo-2-buten-1-yl]methylamino]butyl]-N5-[19-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-15-oxo-4,7,10-trioxa-14-azanonadec-1-

1. Betty Y. CHANG, et al. Companion diagnostics for tec family kinase inhibitor therapy. WO 2014059368 A1.

Calculator

molnova catalog