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KDM5-C49
CAS No. 1596348-16-1
KDM5-C49( KDM5 inhibitor C49 )
Catalog No. M12279 CAS No. 1596348-16-1
KDM5-C49 is a potent, selective KDM5 inhibitor with IC50 of 25, 30 and 59 nM for KDM5A, B and C, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameKDM5-C49
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NoteResearch use only, not for human use.
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Brief DescriptionKDM5-C49 is a potent, selective KDM5 inhibitor with IC50 of 25, 30 and 59 nM for KDM5A, B and C, respectively.
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DescriptionKDM5-C49 is a potent, selective KDM5 inhibitor with IC50 of 25, 30 and 59 nM for KDM5A, B and C, respectively; displays 25-100-fold selectivity over KDM6B, 2-30-fold selectivity over KDM4 family, but with less cell-permeablity.
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In Vitro——
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In Vivo——
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SynonymsKDM5 inhibitor C49
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PathwayChromatin/Epigenetic
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TargetHistone Demethylase
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RecptorHistone Demethylase
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Research Area——
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Indication——
Chemical Information
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CAS Number1596348-16-1
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Formula Weight308.382
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Molecular FormulaC15H24N4O3
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(O)C1=CC=NC(CNCC(N(CCN(C)C)CC)=O)=C1
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Chemical Name2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Johansson C, et. Nat Chem Biol. 2016 Jul;12(7):539-45.
2. Horton JR, et al. Cell Chem Biol. 2016 Jul 21;23(7):769-81.
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