Cart
sales@molnova.com
Home - Products - Microbiology/Virology - HBV - RO6889678

RO6889678

CAS No. 1578153-27-1

RO6889678( RO 6889678 )

Catalog No. M12255 CAS No. 1578153-27-1

RO6889678 is a highly potent inhibitor of HBV capsid formation with attributes that are favorable for targeting the liver, whilst maintaining moderate peripheral exposure.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 161 In Stock
2MG 93 In Stock
5MG 131 In Stock
10MG 188 In Stock
25MG 269 In Stock
50MG 420 In Stock
100MG 618 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    RO6889678
  • Note
    Research use only, not for human use.
  • Brief Description
    RO6889678 is a highly potent inhibitor of HBV capsid formation with attributes that are favorable for targeting the liver, whilst maintaining moderate peripheral exposure.
  • Description
    RO6889678 is a highly potent inhibitor of HBV capsid formation with attributes that are favorable for targeting the liver, whilst maintaining moderate peripheral exposure.HBV InfectionPhase 1 Discontinued.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    RO 6889678
  • Pathway
    Microbiology/Virology
  • Target
    HBV
  • Recptor
    HBV
  • Research Area
    Infection
  • Indication
    HBV Infection

Chemical Information

  • CAS Number
    1578153-27-1
  • Formula Weight
    494.922
  • Molecular Formula
    C21H20ClFN4O5S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C([C@H]1N(CC2=C(C(OC)=O)[C@H](C3=CC=C(F)C=C3Cl)N=C(C4=NC=CS4)N2)CCOC1)O
  • Chemical Name
    (S)-4-(((R)-6-(2-chloro-4-fluorophenyl)-5-(methoxycarbonyl)-2-(thiazol-2-yl)-3,6-dihydropyrimidin-4-yl)methyl)morpholine-3-carboxylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kratochwil NA, et al. J Pharmacol Exp Ther. 2018 Feb 16. pii: jpet.117.245712.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • ccc_R08

    ccc_R08 is an orally available HBV cccDNA inhibitor that reduces extracellular levels of HBV DNA, HBsAg, and HBeAg in a dose-dependent manner. ccc_R08 is investigational for use in the treatment of HBV infections. ccc_R08 has been shown to be effective in the treatment of hepatitis C virus (HCV).

  • Ibandronate sodium

    Ibandronate Sodium is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.

  • IR415

    IR415 is a novel small molecule inhibitor of HBV virus replication that blocks hepatitis B virus X protein (HBx, Kd=2 nM) mediated RNAi suppression.

Sign In Join Free