Cart
sales@molnova.com
Bosentan Hydrate
CAS No. 157212-55-0
Bosentan Hydrate( —— )
Catalog No. M12244 CAS No. 157212-55-0
Bosentan is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 55 | In Stock |
|
| 25MG | 37 | In Stock |
|
| 50MG | 51 | In Stock |
|
| 100MG | 90 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBosentan Hydrate
-
NoteResearch use only, not for human use.
-
Brief DescriptionBosentan is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.
-
DescriptionBosentan is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayGPCR/G Protein
-
TargetEndothelin Receptor
-
RecptorET-B| ET-A
-
Research AreaCardiovascular Disease
-
Indication——
Chemical Information
-
CAS Number157212-55-0
-
Formula Weight569.63
-
Molecular FormulaC??H??N?O?S
-
Purity>98% (HPLC)
-
SolubilityDMSO:93 mg/mL (163.3 mM);Ethanol:2 mg/mL (3.51 mM);Water:<1 mg/Ml
-
SMILESO.COC1=CC=CC=C1OC1=C(OCCO)N=C(N=C1NS(=O)(=O)C1=CC=C(C=C1)C(C)(C)C)C1=NC=CC=N1 |c:4,6,10,16,18,27,29,38,40,t:2,25,36|
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Clozel M, et al. J Pharmacol Exp Ther, 1994, 270(1), 228-235.
molnova catalog
related products
-
SB-209670
SB-209670 is a selective endothelin receptor antagonist that inhibits the activity of ET(B) receptors in rat vascular endothelium and vascular smooth muscle.
-
Sarafotoxin S6c
Highly selective ETB endothelin receptor agonist (Ki values are 0.29 and 28000 nM at ETB and ETA receptors respectively).
-
Ambrisentan
Ambrisentan (BSF 208075;LU 208075) is a highly selective antagonist of the endothelin-1 type A receptor (ETA) for use in the treatment of pulmonary hypertension.
