Cart
sales@molnova.com
Sevelamer HCl
CAS No. 152751-57-0
Sevelamer HCl( —— )
Catalog No. M12141 CAS No. 152751-57-0
Sevelamer HCl is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 28 | In Stock |
|
| 100MG | 36 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 91 | In Stock |
|
| 1G | 120 | In Stock |
|
Biological Information
-
Product NameSevelamer HCl
-
NoteResearch use only, not for human use.
-
Brief DescriptionSevelamer HCl is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption.
-
DescriptionSevelamer HCl is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption.
-
In VitroSevelamer hydrochloride (15 mg/mL; pH=6 or 8) decreases serum levels of gut-derived uremic toxins (such as IAA) or limits the elevation of gut-derived uremic toxins (initial concentration=1 μg/mL or 10 μg/mL).
-
In VivoSevelamer hydrochloride (1% mixed in diet; p.o.; once daily for 5 weeks) reduces Npt2b-deficient mice serum phosphate levels, but fails to reduce the level in uremic WT mice.Sevelamer hydrochloride leads to a significant decrease in osteoclast number in uremic WT mice with a trend toward further decrease in Npt2b-/- mice.Sevelamer hydrochloride leads to a significant increase in Npt2b protein expression.
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
Recptor——
-
Research AreaOther Indications
-
Indication——
Chemical Information
-
CAS Number152751-57-0
-
Formula Weight186.08
-
Molecular Formula(C?H?N . C?H?ClO)x . x HCl
-
Purity>98% (HPLC)
-
SolubilityDMSO:<1 mg/mL; Ethanol:<1 mg/mL; Water:<1 mg/mL
-
SMILESC=CCN.C1C(O1)CCl.Cl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Katsumata K, et al. Kidney Int, 2003, 64(2), 441-450.
molnova catalog
related products
-
Momordicoside A
Momordicoside A is isolated from Momordica charantia L. Momordicoside A has the inhibitory effect on protein tyrosine phosphatase (PTP1B).
-
E-3030
E-3030 free acid is a potent dual activator of peroxisome proliferator-activated receptor (PPAR) alpha and PPARgamma, exhibiting significant antidiabetic and lipid-modulating effects. E-3030 decreases blood glucose, triglyceride, non-esterified fatty acids, and insulin levels, while increasing blood adiponectin levels. E-3030 improves glucose tolerance and shows remarkable triglyceride- and non-high-density lipoprotein cholesterol-lowering effects in animal models.
-
Carbamazepine 10,11-...
Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant carbamazepine.
