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Cortodoxone
CAS No. 152-58-9
Cortodoxone( 11-Deoxycortisol | Cortexolone )
Catalog No. M12133 CAS No. 152-58-9
Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 42 | In Stock |
|
| 25MG | 38 | In Stock |
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| 50MG | 57 | In Stock |
|
| 100MG | 81 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 184 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCortodoxone
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NoteResearch use only, not for human use.
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Brief DescriptionCortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone).
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DescriptionCortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone); exhibits corticosteroid binding characteristics, including DNA binding; 11-deoxycortisol is regulated by the hypothalamus-pituitary axis and responded to acute stress; impedes GABAergic neurotransmission and induces drug-resistant status epilepticus in mice.
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In Vitro——
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In Vivo——
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Synonyms11-Deoxycortisol | Cortexolone
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PathwayEndocrinology/Hormones
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TargetGR
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RecptorGlucocorticoidReceptor
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number152-58-9
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Formula Weight346.4605
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Molecular FormulaC21H30O4
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 33 mg/mL
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SMILESCC12CCC(=O)C=C1CCC3C2CCC4(C3CCC4(C(=O)CO)O)C
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Chemical NamePregn-4-ene-3,20-dione, 17,21-dihydroxy-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Close DA, et al. Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13942-7.
2. Kaminski RM, et al. Neuropharmacology. 2011 Jun;60(7-8):1098-108.
3. Baker ME, et al. Steroids. 2011 Dec 11;76(13):1451-7.
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