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Home - Products - Membrane Transporter/Ion Channel - GAT - U-93631

U-93631

CAS No. 152273-12-6

U-93631( U93631 | U 93631 )

Catalog No. M12126 CAS No. 152273-12-6

A potent GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
25MG 43 In Stock
50MG 63 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    U-93631
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction.
  • Description
    A potent GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction; induce a rapid, time-dependent decay of GABA-induced whole-cell Cl- currents in recombinant GABAA receptors.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    U93631 | U 93631
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    GAT
  • Recptor
    GABA
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    152273-12-6
  • Formula Weight
    299.3676
  • Molecular Formula
    C17H21N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 34 mg/mL
  • SMILES
    O=C(C1=C2N(C=N1)C3=C(C=CC=C3)NC2(C)C)OC(C)(C)C
  • Chemical Name
    Imidazo[1,5-a]quinoxaline-3-carboxylic acid, 4,5-dihydro-4,4-dimethyl-, 1,1-dimethylethyl ester

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dillon GH, et al. Mol Pharmacol. 1993 Oct;44(4):860-5. 2. Dillon GH, et al. J Pharmacol Exp Ther. 1995 Feb;272(2):597-603. 3. Dillon GH, et al. Br J Pharmacol. 1995 Jun;115(3):539-45.
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