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NITD-304

CAS No. 1473450-60-0

NITD-304( NITD304 )

Catalog No. M12025 CAS No. 1473450-60-0

NITD-304 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 15 nM against M tuberculosis H37Rv.

Purity : >98% (HPLC)

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Size	Price / USD	Stock	Quantity
5MG	873	Get Quote
50MG	1782	Get Quote
100MG	2250	Get Quote
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Biological Information

Product Name

NITD-304
Note

Research use only, not for human use.
Brief Description

NITD-304 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 15 nM against M tuberculosis H37Rv.
Description

NITD-304 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 15 nM against M tuberculosis H37Rv; shows potent activity against both drug-sensitive and multidrug-resistant clinical isolates of Mtb; demonstrates effectivity in treating both acute and chronic Mtb infections in mouse efficacy models.
In Vitro

——
In Vivo

——
Synonyms

NITD304
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

1473450-60-0
Formula Weight

339.27
Molecular Formula

C17H20Cl2N2O
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(C(N1)=CC2=C1C=C(Cl)C=C2Cl)NC3CCC(C)(C)CC3
Chemical Name

4,6-dichloro-N-(4,4-dimethylcyclohexyl)-1H-indole-2-carboxamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Rao SP, et al. Sci Transl Med. 2013 Dec 4;5(214):214ra168.

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