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Home - Products - Microbiology/Virology - HCV - BMS-961955

BMS-961955

CAS No. 1431328-92-5

BMS-961955( BMS961955 )

Catalog No. M11828 CAS No. 1431328-92-5

BMS-961955 is an potent, allosteric inhibitor of HCV NS5B polymerase with EC50 of 7.9/4.3 nM for GT 1b/1a replicon respectively.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    BMS-961955
  • Note
    Research use only, not for human use.
  • Brief Description
    BMS-961955 is an potent, allosteric inhibitor of HCV NS5B polymerase with EC50 of 7.9/4.3 nM for GT 1b/1a replicon respectively.
  • Description
    BMS-961955 is an potent, allosteric inhibitor of HCV NS5B polymerase with EC50 of 7.9/4.3 nM for GT 1b/1a replicon respectively; shows weak activity against PXR; displayes significantly enhanced metabolic stability in CLM and HLM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    BMS961955
  • Pathway
    Microbiology/Virology
  • Target
    HCV
  • Recptor
    HCV
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    1431328-92-5
  • Formula Weight
    658.833
  • Molecular Formula
    C37H43FN4O4S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1(CC1)S(=O)(=O)NC(=O)C2=CC3=C(C=C2)C(=C4N3CC5(CC5C6=C4C=CC(=C6)F)C(=O)N7C8CCC7CN(C8)C)C9CCCCC9
  • Chemical Name
    (4bS,5aR)-12-Cyclohexyl-3-fluoro-4b,5,5a,6-tetrahydro-N-[(1-methylcyclopropyl)sulfonyl]-5a-[(3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl]cycloprop[d]indolo[2,1-a][2]benzazepine-9-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zheng BZ, et al. Bioorg Med Chem Lett. 2017 Jun 11. pii: S0960-894X(17)30626-1.
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