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LY305
CAS No. 1430230-83-3
LY305( LY 305 | LY-305 )
Catalog No. M11820 CAS No. 1430230-83-3
LY305 (LY-305) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 2.03 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameLY305
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NoteResearch use only, not for human use.
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Brief DescriptionLY305 (LY-305) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 2.03 nM.
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DescriptionLY305 (LY-305) is a non-steroidal selective androgen receptor modulator (SARM) with Ki of 2.03 nM, demonstrates potent agonist activity in the aforementioned C2C12 cellular assay (EC50=0.499 nM); displays little to no affinity for GR, PR and MR (Ki>800 nM); shows the desired muscle and prostate effects in a preclinical ORX rat model.
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In Vitro——
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In Vivo——
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SynonymsLY 305 | LY-305
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PathwayEndocrinology/Hormones
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TargetAndrogen Receptor (AR)
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RecptorAndrogen Receptor (AR)
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Research Area——
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Indication——
Chemical Information
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CAS Number1430230-83-3
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Formula Weight264.753
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Molecular FormulaC14H17ClN2O
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name2-chloro-4-(((1R,2R)-2-hydroxy-2-methylcyclopentyl)amino)-3-methylbenzonitrile
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Krishnan V, et al. Andrology. 2018 Mar 12. doi: 10.1111/andr.12479.
2. Saeed A, et al. J Med Chem. 2016 Jan 28;59(2):750-5.
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