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BRD 8184

CAS No. 1423058-83-6

BRD 8184( BRD8184 )

Catalog No. M11782 CAS No. 1423058-83-6

BRD 8184 is a potent, selective HDAC6 inhibitor with IC50 of 8 nM.

Purity : >98% (HPLC)

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Biological Information

Product Name

BRD 8184
Note

Research use only, not for human use.
Brief Description

BRD 8184 is a potent, selective HDAC6 inhibitor with IC50 of 8 nM.
Description

BRD 8184 is a potent, selective HDAC6 inhibitor with IC50 of 8 nM, weakly inhibits HDAC2 and HDAC8 (IC50=0.34 and 1.33 uM),has no activity for HDAC4 (IC50>30 uM).
In Vitro

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In Vivo

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Synonyms

BRD8184
Pathway

Cell Cycle/DNA Damage
Target

HDAC
Recptor

HDAC
Research Area

——
Indication

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Chemical Information

CAS Number

1423058-83-6
Formula Weight

285.303
Molecular Formula

C15H15N3O3
Purity

>98% (HPLC)
Solubility

——
SMILES

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Chemical Name

N1-hydroxy-N4-(2-(pyridin-4-yl)ethyl)terephthalamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Wagner FF, et al. J Med Chem. 2013 Feb 28;56(4):1772-6.

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