DBCO-Biotin( —— )

Catalog No. M11748 CAS No. 1418217-95-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

DBCO-Biotin
Note

Research use only, not for human use.
Brief Description

DBCO-Biotin is a Click Chemistry intermidate used for antibody-drug conjugates.
Description

DBCO-Biotin is a Click Chemistry intermidate used for antibody-drug conjugates.
In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vivo

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Synonyms

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Pathway

Antibody Drug Conjugates (ADC)
Target

ADCs Linker/Click Chemistry
Recptor

ADCs Linker/Click Chemistry
Research Area

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Indication

——

CAS Number

1418217-95-4
Formula Weight

502.633
Molecular Formula

C28H30N4O3S
Purity

>98% (HPLC)
Solubility

——
SMILES

C1C2C(C(S1)CCCCC(=O)NCCC(=O)N3CC4=CC=CC=C4C#CC5=CC=CC=C53)NC(=O)N2
Chemical Name

(3aS,4S,6aR)-N-[3-(11,12-Didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide