Cart
sales@molnova.com
(±)-BI-D
CAS No. 1416258-16-6
(±)-BI-D( —— )
Catalog No. M11732 CAS No. 1416258-16-6
A potent, allosteric HIV integrase inhibitor (Kd=34 nM) that binds the LEDGF/p75 binding site on integrase.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 1341 | Get Quote |
|
| 100MG | 1791 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product Name(±)-BI-D
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent, allosteric HIV integrase inhibitor (Kd=34 nM) that binds the LEDGF/p75 binding site on integrase.
-
DescriptionA potent, allosteric HIV integrase inhibitor (Kd=34 nM) that binds the LEDGF/p75 binding site on integrase; inhibits the replication of NL4.3 virus (T124/T125) with EC50 of 51 nM.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMicrobiology/Virology
-
TargetHIV
-
RecptorHIV
-
Research AreaInfection
-
Indication——
Chemical Information
-
CAS Number1416258-16-6
-
Formula Weight405.4862
-
Molecular FormulaC25H27NO4
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESCC1=NC2=CC=CC=C2C(=C1C(C(=O)O)OC(C)(C)C)C3=CC4=C(C=C3)OCCC4
-
Chemical Name3-Quinolineacetic acid, 4-(3,4-dihydro-2H-1-benzopyran-6-yl)-α-(1,1-dimethylethoxy)-2-methyl-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Fader LD, et al. ACS Med Chem Lett. 2014 Apr 16;5(6):711-6.
2. Wang H, et al. Nucleic Acids Res. 2012 Dec;40(22):11518-30.
molnova catalog
related products
-
MK-8591
MK-8591 (Islatravir, MK8591, EFdA) is a nucleoside analog that exhibits remarkable potency against wild-type and drug-resistant HIVs.
-
Peptide T
Peptide T is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a synthetic octapeptide whose possible mechanism of action is the competitive inhibition of gp120 to the CD4 receptor as well as binding to vasointestinal peptide receptors and inhibiting cytokine action.
-
NBD-557
A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction; inhibits the fusion between HIV-1NL4-3-luc pseudotyped virus expressing HIV-1HXB2 (X4-tropic) envelope and U87-T4-CXCR4 cells with IC50 of 9.7 uM.
