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CDK9-IN-1
CAS No. 1415559-43-1
CDK9-IN-1( —— )
Catalog No. M11724 CAS No. 1415559-43-1
CDK9-IN-1 is a potent, selective CDK9 inhibitor with IC50 of 39 nM (CDK9/CycT1), >10-fold selectivity over CDK4 and >100-fold over CDK1/2/3/5/6/7, inhibits HIV-1 replication in cellular assays.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameCDK9-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionCDK9-IN-1 is a potent, selective CDK9 inhibitor with IC50 of 39 nM (CDK9/CycT1), >10-fold selectivity over CDK4 and >100-fold over CDK1/2/3/5/6/7, inhibits HIV-1 replication in cellular assays.
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DescriptionCDK9-IN-1 is a potent, selective CDK9 inhibitor with IC50 of 39 nM (CDK9/CycT1), >10-fold selectivity over CDK4 and >100-fold over CDK1/2/3/5/6/7, inhibits HIV-1 replication in cellular assays.
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In VitroCDK9-IN-1 is a potent CDK9 inhibitor that shows high activity against HIV-1 replication.
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetCDK
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RecptorCDK
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number1415559-43-1
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Formula Weight499.541
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Molecular FormulaC26H21N5O4S
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCC1=C(C=C(C=C1)NC2=NC=NC(=C2)C3=CC(=CC=C3)N4C(=O)C5=CC=CC=C5C4=O)NS(=O)(=O)C
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Chemical NameN-(5-(6-(3-(1,3-dioxoisoindolin-2-yl)phenyl)pyrimidin-4-ylamino)-2-methylphenyl)methanesulfonamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Németh G, et al. Curr Med Chem. 2011;18(3):342-58.
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