Bio-AMS( —— )

Catalog No. M11642 CAS No. 1393881-52-1

Bio-AMS is a chemical inhibitor of Mycobacterium tuberculosis biotin protein ligase ( MtBPL) with Kd of 0.865 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Bio-AMS
Note

Research use only, not for human use.
Brief Description

Bio-AMS is a chemical inhibitor of Mycobacterium tuberculosis biotin protein ligase ( MtBPL) with Kd of 0.865 nM.
Description

Bio-AMS is a chemical inhibitor of Mycobacterium tuberculosis biotin protein ligase ( MtBPL) with Kd of 0.865 nM; possesses selective activity against Mycobacterium tuberculosis ( Mtb) and arrests fatty acid and lipid biosynthesis, enhances tuberculosis chemotherapy (rifampicin and ethambutol).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

1393881-52-1
Formula Weight

571.628
Molecular Formula

C20H29N9O7S2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (174.94 mM)
SMILES

——
Chemical Name

5'-[ N-(d-biotinoyl)sulfamoyl]amino-5'-deoxyadenosine

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Tiwari D, et al. Sci Transl Med. 2018 Apr 25;10(438). pii: eaal1803. 2. Bockman MR, et al. ACS Infect Dis. 2018 Apr 17. doi: 10.1021/acsinfecdis.8b00038.

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