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Bio-AMS

CAS No. 1393881-52-1

Bio-AMS( —— )

Catalog No. M11642 CAS No. 1393881-52-1

Bio-AMS is a chemical inhibitor of Mycobacterium tuberculosis biotin protein ligase ( MtBPL) with Kd of 0.865 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Bio-AMS
  • Note
    Research use only, not for human use.
  • Brief Description
    Bio-AMS is a chemical inhibitor of Mycobacterium tuberculosis biotin protein ligase ( MtBPL) with Kd of 0.865 nM.
  • Description
    Bio-AMS is a chemical inhibitor of Mycobacterium tuberculosis biotin protein ligase ( MtBPL) with Kd of 0.865 nM; possesses selective activity against Mycobacterium tuberculosis ( Mtb) and arrests fatty acid and lipid biosynthesis, enhances tuberculosis chemotherapy (rifampicin and ethambutol).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1393881-52-1
  • Formula Weight
    571.628
  • Molecular Formula
    C20H29N9O7S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (174.94 mM)
  • SMILES
    ——
  • Chemical Name
    5'-[ N-(d-biotinoyl)sulfamoyl]amino-5'-deoxyadenosine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Tiwari D, et al. Sci Transl Med. 2018 Apr 25;10(438). pii: eaal1803. 2. Bockman MR, et al. ACS Infect Dis. 2018 Apr 17. doi: 10.1021/acsinfecdis.8b00038.
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