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EPZ004777 HCl
CAS No. 1380316-03-9
EPZ004777 HCl ( —— )
Catalog No. M11571 CAS No. 1380316-03-9
EPZ004777 hydrochloride is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameEPZ004777 HCl
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NoteResearch use only, not for human use.
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Brief DescriptionEPZ004777 hydrochloride is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.
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DescriptionEPZ004777 hydrochloride is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetHMTase
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RecptorDOT1L
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1380316-03-9
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Formula Weight576.13
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Molecular FormulaC??H??ClN?O?
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Purity>98% (HPLC)
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SolubilityDMSO:Soluble
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SMILESCC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=CC4=C3N=CN=C4N)O)O.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Chen L, et al. Leukemia. 2013, 27(4), 813-822.
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