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Ubrogepant
CAS No. 1374248-77-7
Ubrogepant( MK-1602 | MK1602 )
Catalog No. M11544 CAS No. 1374248-77-7
Ubrogepant (MK-1602) is a novel potent, selective, oral calcitonin gene-related peptide receptor (CGRP) antagonist for acute treatment of migraine.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 455 | In Stock |
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| 5MG | 377 | In Stock |
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| 10MG | 597 | In Stock |
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| 25MG | 929 | In Stock |
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| 50MG | 1200 | In Stock |
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| 100MG | 1646 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameUbrogepant
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NoteResearch use only, not for human use.
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Brief DescriptionUbrogepant (MK-1602) is a novel potent, selective, oral calcitonin gene-related peptide receptor (CGRP) antagonist for acute treatment of migraine.
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DescriptionUbrogepant (MK-1602) is a novel potent, selective, oral calcitonin gene-related peptide receptor (CGRP) antagonist for acute treatment of migraine.Migraine Phase 3 Clinical.
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In Vitro——
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In Vivo——
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SynonymsMK-1602 | MK1602
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PathwayGPCR/G Protein
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TargetCGRP Receptor
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RecptorCGRP Receptor
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Research AreaNeurological Disease
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IndicationMigraine
Chemical Information
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CAS Number1374248-77-7
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Formula Weight549.554
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Molecular FormulaC29H26F3N5O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (454.93 mM)
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SMILESO=C(C1=CN=C2C(C[C@@]3(C4=CC=CN=C4NC3=O)C2)=C1)N[C@@H]5C(N(CC(F)(F)F)[C@H](C)[C@H](C6=CC=CC=C6)C5)=O
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Chemical Name(3'S)-1',2',5,7-Tetrahydro-N-[(3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-piperidinyl]-2'-oxospiro[6H-cyclopenta[b]pyridine-6,3'-[3H]pyrrolo[2,3-b]pyridine]-3-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Li CC, et al. J Clin Pharmacol. 2017 Nov 14. doi: 10.1002/jcph.1021.
2. Holland PR, et al. Neurotherapeutics. 2018 Apr;15(2):304-312.
3. Voss T, et al. Cephalalgia. 2016 Aug;36(9):887-98.
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